SANTA CLARA, Calif. — Kyler Murray used the new toy Arizona got him this offseason to get his second season off to a rousing start.

Murray connected on 14 passes to newcomer DeAndre Hopkins, including the throw that set up Kenyan Drake’s go-ahead 1-yard score with 5:03 to play that led the Cardinals over the San Francisco 49ers 24-20 on Sunday.

Murray threw for 230 yards and a touchdown and ran for 91 yards and another score to help the Cardinals overcome a pair of fourth-quarter deficits to beat the defending NFC champion 49ers in a smoky opener at an empty stadium.